Honokiol-Mediated Mitophagy Ameliorates Postoperative Cognitive Impairment Induced by Surgery/Sevoflurane via Inhibiting the Activation of NLRP3 Inflammasome in the Hippocampus

BACKGROUND: The potential mechanism of postoperative cognitive impairment is still largely unclear. The activation of NLRP3 inflammasome had been reported to be involved in neurodegenerative diseases, including postoperative cognitive change, and is closely related to mitochondrial ROS and mitophagy...

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Detalles Bibliográficos
Autores principales: Ye, Ji-Shi, Chen, Lei, Lu, Ya-Yuan, Lei, Shao-Qing, Peng, Mian, Xia, Zhong-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409065/
https://www.ncbi.nlm.nih.gov/pubmed/30918581
http://dx.doi.org/10.1155/2019/8639618

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