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In-silico Evaluation of Rare Codons and their Positions in the Structure of ATP8b1 Gene
BACKGROUND: Progressive familial intrahepatic cholestases (PFIC) are a spectrum of autosomal progressive liver diseases developing to end-stage liver disease. ATP8B1 deficiency caused by mutations in ATP8B1 gene encoding a P-type ATPase leads to PFIC1. The gene for PFIC1 has been mapped on a 19-cM r...
Autores principales: | M., Zarenezhad, S.M., Dehghani, F., Ejtehadi, M.R., Fattahi, M., Mortazavi, S.M.B., Tabei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Journal of Biomedical Physics and Engineering
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409373/ https://www.ncbi.nlm.nih.gov/pubmed/30881940 |
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