Chemical Conversion of Human Fetal Astrocytes into Neurons through Modulation of Multiple Signaling Pathways

We have previously developed a cocktail of nine small molecules to convert human fetal astrocytes into neurons, but a nine-molecule recipe is difficult for clinical applications. Here, we identify a chemical formula with only three to four small molecules for astrocyte-to-neuron conversion. We demon...

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Detalles Bibliográficos
Autores principales: Yin, Jiu-Chao, Zhang, Lei, Ma, Ning-Xin, Wang, Yue, Lee, Grace, Hou, Xiao-Yi, Lei, Zhuo-Fan, Zhang, Feng-Yu, Dong, Feng-Ping, Wu, Gang-Yi, Chen, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409415/
https://www.ncbi.nlm.nih.gov/pubmed/30745031
http://dx.doi.org/10.1016/j.stemcr.2019.01.003

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