Cargando…
Genomic Characterization of Orf Virus Strain D1701-V (Parapoxvirus) and Development of Novel Sites for Multiple Transgene Expression
The Orf virus (ORFV; Parapoxvirus) strain D1701 with an attenuated phenotype and excellent immunogenic capacity is successfully used for the generation of recombinant vaccines against different viral infections. Adaption for growth in Vero cells was accompanied by additional major genomic changes re...
Autores principales: | Rziha, Hanns-Joachim, Büttner, Mathias, Müller, Melanie, Salomon, Ferdinand, Reguzova, Alena, Laible, Dominic, Amann, Ralf |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409557/ https://www.ncbi.nlm.nih.gov/pubmed/30704093 http://dx.doi.org/10.3390/v11020127 |
Ejemplares similares
-
Orf Virus-Based Vaccine Vector D1701-V Induces Strong CD8+ T Cell Response against the Transgene but Not against ORFV-Derived Epitopes
por: Reguzova, Alena, et al.
Publicado: (2020) -
A Novel Orf Virus D1701-VrV-Based Dengue Virus (DENV) Vaccine Candidate Expressing HLA-Specific T Cell Epitopes: A Proof-of-Concept Study
por: Reguzova, Alena, et al.
Publicado: (2021) -
New Orf Virus (Parapoxvirus) Recombinant Expressing H5 Hemagglutinin Protects Mice against H5N1 and H1N1 Influenza A Virus
por: Rohde, Jörg, et al.
Publicado: (2013) -
Orf Virus-Based Vectors Preferentially Target Professional Antigen-Presenting Cells, Activate the STING Pathway and Induce Strong Antigen-Specific T Cell Responses
por: Müller, Melanie, et al.
Publicado: (2022) -
Orf virus interferes with MHC class I surface expression by targeting vesicular transport and Golgi
por: Emschermann, Frederic, et al.
Publicado: (2012)