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Applying Supercritical Fluid Technology to Prepare Ibuprofen Solid Dispersions with Improved Oral Bioavailability
In this study, supercritical fluid (SCF) technology was applied to prepare reliable solid dispersions of pharmaceutical compounds with limited bioavailability using ibuprofen (IBU) as a model compound. Solid-state characterization of the dispersions was conducted by differential scanning calorimetry...
Autores principales: | Han, Fei, Zhang, Wei, Wang, Ying, Xi, Ziyue, Chen, Lu, Li, Sanming, Xu, Lu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409573/ https://www.ncbi.nlm.nih.gov/pubmed/30717471 http://dx.doi.org/10.3390/pharmaceutics11020067 |
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