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Applying Supercritical Fluid Technology to Prepare Ibuprofen Solid Dispersions with Improved Oral Bioavailability

In this study, supercritical fluid (SCF) technology was applied to prepare reliable solid dispersions of pharmaceutical compounds with limited bioavailability using ibuprofen (IBU) as a model compound. Solid-state characterization of the dispersions was conducted by differential scanning calorimetry...

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Detalles Bibliográficos
Autores principales: Han, Fei, Zhang, Wei, Wang, Ying, Xi, Ziyue, Chen, Lu, Li, Sanming, Xu, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409573/
https://www.ncbi.nlm.nih.gov/pubmed/30717471
http://dx.doi.org/10.3390/pharmaceutics11020067

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