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Improved Dissolution and Oral Bioavailability of Valsartan Using a Solidified Supersaturable Self-Microemulsifying Drug Delivery System Containing Gelucire(®) 44/14

To improve the dissolution and oral bioavailability of valsartan (VST), we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMED) composed of Capmul(®) MCM (oil), Tween(®) 80 (surfactant), Transcutol(®) P (cosurfactant), and Poloxamer 407 (precipitation inhibitor)...

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Detalles Bibliográficos
Autores principales:	Shin, Dong Jun, Chae, Bo Ram, Goo, Yoon Tae, Yoon, Ho Yub, Kim, Chang Hyun, Sohn, Se Il, Oh, Dongho, Lee, Ahram, Song, Seh Hyon, Choi, Young Wook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409713/ https://www.ncbi.nlm.nih.gov/pubmed/30708963 http://dx.doi.org/10.3390/pharmaceutics11020058

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