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Adeno-Associated Virus (AAV) Versus Immune Response

Decades ago, Friedmann and Roblin postulated several barriers to gene therapy, including tissue targeting, delivery across the blood–brain barrier (BBB), and host immune responses. These issues remain pertinent till today. Since then, several advances have been made in elucidating structures of aden...

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Detalles Bibliográficos
Autores principales:	Rabinowitz, Joseph, Chan, Ying Kai, Samulski, Richard Jude
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409805/ https://www.ncbi.nlm.nih.gov/pubmed/30691064 http://dx.doi.org/10.3390/v11020102

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