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The Cancer Aneuploidy Paradox: In the Light of Evolution

Aneuploidy should compromise cellular proliferation but paradoxically favours tumour progression and poor prognosis. Here, we consider this paradox in terms of our most recent observations of chemo/radio-resistant cells undergoing reversible polyploidy. The latter perform the segregation of two pare...

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Detalles Bibliográficos
Autores principales:	Salmina, Kristine, Huna, Anda, Kalejs, Martins, Pjanova, Dace, Scherthan, Harry, Cragg, Mark S., Erenpreisa, Jekaterina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409809/ https://www.ncbi.nlm.nih.gov/pubmed/30691027 http://dx.doi.org/10.3390/genes10020083

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