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Biopharmaceutical Development of a Bifonazole Multiple Emulsion for Enhanced Epidermal Delivery
Efficient topical delivery of imidazolic antifungals faces the challenge of overcoming its limited water solubility and its required long-lasting duration of treatments. In this paper, a hydrophilic multiple emulsion (ME) of Bifonazole (BFZ) is shown to maximize its skin retention, minimize its skin...
Autores principales: | Suñer-Carbó, Joaquim, Calpena-Campmany, Ana, Halbaut-Bellowa, Lyda, Clares-Naveros, Beatriz, Rodriguez-Lagunas, María José, Barbolini, Elena, Zamarbide-Losada, Joanna, Boix-Montañés, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409818/ https://www.ncbi.nlm.nih.gov/pubmed/30717419 http://dx.doi.org/10.3390/pharmaceutics11020066 |
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