Cargando…

Scleroderma-like syndrome in a woman with silicone breast implants – case report and critical review of the literature

Various silicon compounds have been reported to stimulate autoimmune reactions in the human body. Based on case reports, a possible causal association between silicone breast implants and systemic sclerosis has been suggested since the end of the 1970s. Although the relationship between systemic scl...

Descripción completa

Detalles Bibliográficos
Autores principales: Wroński, Jakub, Bonek, Krzysztof, Stanisławska-Biernat, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409829/
https://www.ncbi.nlm.nih.gov/pubmed/30858632
http://dx.doi.org/10.5114/reum.2019.83241
_version_ 1783402078900584448
author Wroński, Jakub
Bonek, Krzysztof
Stanisławska-Biernat, Ewa
author_facet Wroński, Jakub
Bonek, Krzysztof
Stanisławska-Biernat, Ewa
author_sort Wroński, Jakub
collection PubMed
description Various silicon compounds have been reported to stimulate autoimmune reactions in the human body. Based on case reports, a possible causal association between silicone breast implants and systemic sclerosis has been suggested since the end of the 1970s. Although the relationship between systemic sclerosis and silicone breast implants has been intensely investigated, no clear evidence of such an association has ever been found in epidemiological studies. Instead, it is now proposed that silicone breast implants can induce nonspecific symptoms of inflammatory diseases, despite not fulfilling the diagnostic criteria for a specific autoimmune disease. This phenomenon was named autoimmune syndrome induced by adjuvants (ASIA syndrome). ASIA syndrome is worth considering in the differential diagnosis in rheumatology patients. In this paper, we present a case of the scleroderma-like syndrome in a 48-year-old woman with a broken silicone breast implant and a review the current literature on this issue.
format Online
Article
Text
id pubmed-6409829
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie
record_format MEDLINE/PubMed
spelling pubmed-64098292019-03-11 Scleroderma-like syndrome in a woman with silicone breast implants – case report and critical review of the literature Wroński, Jakub Bonek, Krzysztof Stanisławska-Biernat, Ewa Reumatologia Case Report Various silicon compounds have been reported to stimulate autoimmune reactions in the human body. Based on case reports, a possible causal association between silicone breast implants and systemic sclerosis has been suggested since the end of the 1970s. Although the relationship between systemic sclerosis and silicone breast implants has been intensely investigated, no clear evidence of such an association has ever been found in epidemiological studies. Instead, it is now proposed that silicone breast implants can induce nonspecific symptoms of inflammatory diseases, despite not fulfilling the diagnostic criteria for a specific autoimmune disease. This phenomenon was named autoimmune syndrome induced by adjuvants (ASIA syndrome). ASIA syndrome is worth considering in the differential diagnosis in rheumatology patients. In this paper, we present a case of the scleroderma-like syndrome in a 48-year-old woman with a broken silicone breast implant and a review the current literature on this issue. Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie 2019-02-28 2019 /pmc/articles/PMC6409829/ /pubmed/30858632 http://dx.doi.org/10.5114/reum.2019.83241 Text en Copyright: © 2019 Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Case Report
Wroński, Jakub
Bonek, Krzysztof
Stanisławska-Biernat, Ewa
Scleroderma-like syndrome in a woman with silicone breast implants – case report and critical review of the literature
title Scleroderma-like syndrome in a woman with silicone breast implants – case report and critical review of the literature
title_full Scleroderma-like syndrome in a woman with silicone breast implants – case report and critical review of the literature
title_fullStr Scleroderma-like syndrome in a woman with silicone breast implants – case report and critical review of the literature
title_full_unstemmed Scleroderma-like syndrome in a woman with silicone breast implants – case report and critical review of the literature
title_short Scleroderma-like syndrome in a woman with silicone breast implants – case report and critical review of the literature
title_sort scleroderma-like syndrome in a woman with silicone breast implants – case report and critical review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409829/
https://www.ncbi.nlm.nih.gov/pubmed/30858632
http://dx.doi.org/10.5114/reum.2019.83241
work_keys_str_mv AT wronskijakub sclerodermalikesyndromeinawomanwithsiliconebreastimplantscasereportandcriticalreviewoftheliterature
AT bonekkrzysztof sclerodermalikesyndromeinawomanwithsiliconebreastimplantscasereportandcriticalreviewoftheliterature
AT stanisławskabiernatewa sclerodermalikesyndromeinawomanwithsiliconebreastimplantscasereportandcriticalreviewoftheliterature