Cell Cycle Arrest and Cytotoxic Effects of SAHA and RG7388 Mediated through p21(WAF1/CIP1) and p27(KIP1) in Cancer Cells

Background and Objective: Alterations in gene expressions are often due to epigenetic modifications that can have a significant influence on cancer development, growth, and progression. Lately, histone deacetylase inhibitors (HDACi) such as suberoylanilide hydroxamic acid (SAHA, or vorinostat, MK068...

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Detalles Bibliográficos
Autores principales: Natarajan, Umamaheswari, Venkatesan, Thiagarajan, Radhakrishnan, Vijayaraghavan, Samuel, Shila, Rasappan, Periannan, Rathinavelu, Appu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409969/
https://www.ncbi.nlm.nih.gov/pubmed/30700046
http://dx.doi.org/10.3390/medicina55020030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409969/
https://www.ncbi.nlm.nih.gov/pubmed/30700046
http://dx.doi.org/10.3390/medicina55020030

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