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Insights into Catalytic and tRNA Recognition Mechanism of the Dual-Specific tRNA Methyltransferase from Thermococcus kodakarensis

The tRNA methyltransferase Trm10, conserved throughout Eukarya and Archaea, catalyzes N1-methylation of purine residues at position 9 using S-adenosyl methionine as the methyl donor. The Trm10 family exhibits diverse target nucleotide specificity, with some homologs that are obligate m(1)G(9) or m(1...

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Detalles Bibliográficos
Autores principales:	Krishnamohan, Aiswarya, Dodbele, Samantha, Jackman, Jane E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410153/ https://www.ncbi.nlm.nih.gov/pubmed/30704107 http://dx.doi.org/10.3390/genes10020100

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