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In Silico Identification and Experimental Validation of (−)-Muqubilin A, a Marine Norterpene Peroxide, as PPARα/γ-RXRα Agonist and RARα Positive Allosteric Modulator

The nuclear receptors (NRs) RARα, RXRα, PPARα, and PPARγ represent promising pharmacological targets for the treatment of neurodegenerative diseases. In the search for molecules able to simultaneously target all the above-mentioned NRs, we screened an in-house developed molecular database using a li...

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Detalles Bibliográficos
Autores principales:	D’Aniello, Enrico, Iannotti, Fabio Arturo, Falkenberg, Lauren G., Martella, Andrea, Gentile, Alessandra, De Maio, Fabrizia, Ciavatta, Maria Letizia, Gavagnin, Margherita, Waxman, Joshua S., Di Marzo, Vincenzo, Amodeo, Pietro, Vitale, Rosa Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410278/ https://www.ncbi.nlm.nih.gov/pubmed/30759808 http://dx.doi.org/10.3390/md17020110

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