Cargando…

Isolation, Structure Elucidation and Biological Evaluation of Lagunamide D: A New Cytotoxic Macrocyclic Depsipeptide from Marine Cyanobacteria

Lagunamide D, a new cytotoxic macrocyclic depsipeptide, was discovered from a collection of marine cyanobacteria from Loggerhead Key in the Dry Tortugas, Florida. An intramolecular ester exchange was observed, where the 26-membered macrocycle could contract to a 24-membered compound via acyl migrati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Danmeng, Putra, Masteria Y., Ye, Tao, Paul, Valerie J., Luesch, Hendrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410412/ https://www.ncbi.nlm.nih.gov/pubmed/30717076 http://dx.doi.org/10.3390/md17020083

Ejemplares similares

Biochemical Studies of the Lagunamides, Potent Cytotoxic Cyclic Depsipeptides from the Marine Cyanobacterium Lyngbya majuscula
por: Tripathi, Ashootosh, et al.
Publicado: (2012)

Isolation and Biological Activity of Iezoside and Iezoside B, SERCA Inhibitors from Floridian Marine Cyanobacteria
por: Kokkaliari, Sofia, et al.
Publicado: (2023)

Lyngbyastatins 8–10, Elastase Inhibitors with Cyclic Depsipeptide Scaffolds Isolated from the Marine Cyanobacterium Lyngbya semiplena
por: Kwan, Jason C., et al.
Publicado: (2009)

Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles
por: Spinck, Martin, et al.
Publicado: (2022)

Marine Organisms as a Prolific Source of Bioactive Depsipeptides
por: Zeng, Mingyuan, et al.
Publicado: (2023)

Grassypeptolides A−C, Cytotoxic Bis-thiazoline Containing Marine Cyclodepsipeptides
por: Kwan, Jason C., et al.
Publicado: (2010)

Applying molecular networking for targeted isolation of depsipeptides
por: Lin, Xiao, et al.
Publicado: (2021)

Chemical Diversity and Biological Activity of Secondary Metabolites Isolated from Indonesian Marine Invertebrates
por: Izzati, Fauzia, et al.
Publicado: (2021)

Bioactive Peptides and Depsipeptides with Anticancer Potential: Sources from Marine Animals
por: Suarez-Jimenez, Guadalupe-Miroslava, et al.
Publicado: (2012)

SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A
por: Cassilly, Chelsi D., et al.
Publicado: (2016)

Marine-Derived Indole Alkaloids and Their Biological and Pharmacological Activities †
por: Wibowo, Joko Tri, et al.
Publicado: (2021)

Structure–Activity Relationship of Cytotoxic Natural Products from Indonesian Marine Sponges
por: Panggabean, Jonathan A., et al.
Publicado: (2022)

Antimicrobial and Cytotoxic Assessment of Marine Cyanobacteria - Synechocystis and Synechococcus
por: Martins, R. F., et al.
Publicado: (2008)

Chromopeptide A, a highly cytotoxic depsipeptide from the marine sediment-derived bacterium Chromobacterium sp. HS-13-94
por: Zhou, Zhenfang, et al.
Publicado: (2015)

Depsipeptide Companeramides from a Panamanian Marine Cyanobacterium Associated with the Coibamide Producer
por: Vining, Oliver B., et al.
Publicado: (2015)

Chemical and Metagenomic Studies of the Lethal Black Band Disease of Corals Reveal Two Broadly Distributed, Redox-Sensitive Mixed Polyketide/Peptide Macrocycles
por: Gunasekera, Sarath P., et al.
Publicado: (2019)

Structural Diversity and Biological Activities of Cyclic Depsipeptides from Fungi
por: Wang, Xiaohan, et al.
Publicado: (2018)

Synthetic biology in marine cyanobacteria: Advances and challenges
por: Bourgade, Barbara, et al.
Publicado: (2022)

Inhibition of Virulence Gene Expression in Staphylococcus aureus by Novel Depsipeptides from a Marine Photobacterium
por: Mansson, Maria, et al.
Publicado: (2011)

Marine-Derived Macrocyclic Alkaloids (MDMAs): Chemical and Biological Diversity
por: Althagbi, Hanan I., et al.
Publicado: (2020)

Marine sponge depsipeptide increases gap junction length in HTC cells transfected with Cx43–GFP
por: Rangel, Marisa, et al.
Publicado: (2010)

Transcription inhibition by the depsipeptide antibiotic salinamide A
por: Degen, David, et al.
Publicado: (2014)

A Survey of Didemnin Depsipeptide Production in Tistrella
por: Stankey, Robert J., et al.
Publicado: (2023)

Origin of marine planktonic cyanobacteria
por: Sánchez-Baracaldo, Patricia
Publicado: (2015)

Hormaomycins B and C: New Antibiotic Cyclic Depsipeptides from a Marine Mudflat-Derived Streptomyces sp.
por: Bae, Munhyung, et al.
Publicado: (2015)

Benderamide A, a Cyclic Depsipeptide from a Singapore Collection of Marine Cyanobacterium cf. Lyngbya sp.
por: Ding, Chi Ying Gary, et al.
Publicado: (2018)

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo
por: Søgaard, Ole S., et al.
Publicado: (2015)

Actinomycin X2, an Antimicrobial Depsipeptide from Marine-Derived Streptomyces cyaneofuscatus Applied as a Good Natural Dye for Silk Fabric
por: Chen, Wei, et al.
Publicado: (2021)

Unique Polyhalogenated Peptides from the Marine Sponge Ircinia sp.
por: Fernández, Rogelio, et al.
Publicado: (2020)

Elucidation of master allostery essential for circadian clock oscillation in cyanobacteria
por: Furuike, Yoshihiko, et al.
Publicado: (2022)

Differential Toxicity of Cyanobacteria Isolated from Marine Sponges towards Echinoderms and Crustaceans
por: Regueiras, Ana, et al.
Publicado: (2018)

New Peptides Isolated from Marine Cyanobacteria, an Overview over the Past Decade
por: Mi, Yue, et al.
Publicado: (2017)

Synthesis of Natural and Unnatural Cyclooligomeric Depsipeptides Enabled by Flow Chemistry
por: Lücke, Daniel, et al.
Publicado: (2016)

Orthogonally Stimulated Assembly/Disassembly of Depsipeptides by Rational Chemical Design
por: Pieszka, Michaela, et al.
Publicado: (2019)

Zhaoshumycins A and B, Two Unprecedented Antimycin-Type Depsipeptides Produced by the Marine-Derived Streptomyces sp. ITBB-ZKa6
por: Guo, Zhikai, et al.
Publicado: (2021)

Intramolecular Modulation of Serine Protease Inhibitor Activity in a Marine Cyanobacterium with Antifeedant Properties
por: Matthew, Susan, et al.
Publicado: (2010)

Developmental Biology in Cyanobacteria
por: Herrero, Antonia, et al.
Publicado: (2019)

Iron Utilization in Marine Cyanobacteria and Eukaryotic Algae
por: Morrissey, Joe, et al.
Publicado: (2012)

Global distribution and diversity of marine euendolithic cyanobacteria
por: Wyness, Adam J., et al.
Publicado: (2022)

Kempopeptin C, a Novel Marine-Derived Serine Protease Inhibitor Targeting Invasive Breast Cancer
por: Al-Awadhi, Fatma H., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ubdfj4uvl5n93ju3836o9uc7lg