Cargando…
Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue
[F-18]-MK-6240, a novel tau positron emission tomography (PET) tracer recently discovered for the in vivo detection of neurofibrillary tangles, has the potential to improve diagnostic accuracy in the detection of Alzheimer disease. We have examined regional and substrate-specific binding patterns as...
Autores principales: | Aguero, Cinthya, Dhaynaut, Maeva, Normandin, Marc D., Amaral, Ana C., Guehl, Nicolas J., Neelamegam, Ramesh, Marquie, Marta, Johnson, Keith A., El Fakhri, Georges, Frosch, Matthew P., Gomez-Isla, Teresa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410510/ https://www.ncbi.nlm.nih.gov/pubmed/30857558 http://dx.doi.org/10.1186/s40478-019-0686-6 |
Ejemplares similares
-
Characterization of MK6240, a tau PET tracer, in autopsy brain tissue from Alzheimer’s disease cases
por: Malarte, Mona-Lisa, et al.
Publicado: (2020) -
(18)F-MK-6240 tau-PET in genetic frontotemporal dementia
por: Levy, Jake P, et al.
Publicado: (2021) -
Optimizing quantification of MK6240 tau PET in unimpaired older adults
por: Harrison, Theresa M., et al.
Publicado: (2023) -
Dosimetry and efficacy of a tau PET tracer [(18)F]MK-6240 in Japanese healthy elderly and patients with Alzheimer’s disease
por: Ohnishi, Akihito, et al.
Publicado: (2022) -
Cryo-EM structure of Alzheimer’s disease tau filaments with PET ligand MK-6240
por: Kunach, Peter, et al.
Publicado: (2023)