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Pharmacological inhibition of the triggering receptor expressed on myeloid cells‐1 limits reperfusion injury in a porcine model of myocardial infarction

AIMS: Limitation of ischemia/reperfusion injury is a major therapeutic target after acute myocardial infarction (AMI). Toll‐like receptors are implicated in the inflammatory response that occurs during reperfusion. The triggering receptor expressed on myeloid cells (TREM)‐1 acts as an amplifier of t...

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Detalles Bibliográficos
Autores principales: Lemarié, Jérémie, Boufenzer, Amir, Popovic, Batric, Tran, Nguyen, Groubatch, Frederique, Derive, Marc, Labroca, Pierre, Barraud, Damien, Gibot, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410538/
https://www.ncbi.nlm.nih.gov/pubmed/28834656
http://dx.doi.org/10.1002/ehf2.12029