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Blood pressure control in treated hypertensive Middle Eastern patients: a post hoc analysis based on JNC8 definitions

BACKGROUND: Long-term blood pressure (BP) control is challenging due to the asymptomatic nature of hypertension and poor treatment adherence among patients. We conducted a post hoc analysis to assess “target BP” attainment and maintenance and to identify their associated factors in a sample of hyper...

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Autores principales: Alhaddad, Imad A, Hamoui, Omar, Hammoudeh, Ayman, Mallat, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410753/
https://www.ncbi.nlm.nih.gov/pubmed/30881006
http://dx.doi.org/10.2147/VHRM.S188981
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author Alhaddad, Imad A
Hamoui, Omar
Hammoudeh, Ayman
Mallat, Samir
author_facet Alhaddad, Imad A
Hamoui, Omar
Hammoudeh, Ayman
Mallat, Samir
author_sort Alhaddad, Imad A
collection PubMed
description BACKGROUND: Long-term blood pressure (BP) control is challenging due to the asymptomatic nature of hypertension and poor treatment adherence among patients. We conducted a post hoc analysis to assess “target BP” attainment and maintenance and to identify their associated factors in a sample of hypertensive Middle Eastern patients. METHODS: We previously conducted an observational study between May 2011 and September 2012 to assess antihypertensive treatment adherence and its determinants in a sample of 1,470 hypertensive patients in Lebanon and Jordan. The study consisted of 3 visits: at baseline, 3 months, and 6 months, where BP control, health-related quality of life, and treatment adherence were assessed. This post hoc analysis of data from the ADHERENCE study examined BP control in terms of target attainment at 3 months and 6 months, and target maintenance at 6 months in treatment-eligible patients as well as the determinants of BP control including the impact of the new JNC8 (Eighth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure) guideline on treatment eligibility and target BP attainment in these patients. RESULTS: Based on JNC8 definitions, our results revealed that 81.2% of patients achieved BP control at 6 months. At 3 months, 62.2% achieved BP control; of those, only 57.5% maintained BP control till 6 months. Factors associated with higher BP target attainment at 3 months were higher educational level, new hypertension diagnosis, older age, and lower waist circumference, systolic BP, and diastolic BP at baseline. Factors associated with higher BP target attainment at 6 months were Lebanese nationality, new hypertension diagnosis, absence of chronic kidney disease, lower systolic BP at baseline, reaching BP target at 3 months, and having a BP target of <150/90 mmHg. CONCLUSION: Older age, higher education levels, recent hypertension diagnosis, early achievement of target BP, and having milder disease at baseline were associated with better BP control. Moreover, JNC8 guideline reduced the number of treatment-eligible patients and increased BP target attainment.
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spelling pubmed-64107532019-03-16 Blood pressure control in treated hypertensive Middle Eastern patients: a post hoc analysis based on JNC8 definitions Alhaddad, Imad A Hamoui, Omar Hammoudeh, Ayman Mallat, Samir Vasc Health Risk Manag Original Research BACKGROUND: Long-term blood pressure (BP) control is challenging due to the asymptomatic nature of hypertension and poor treatment adherence among patients. We conducted a post hoc analysis to assess “target BP” attainment and maintenance and to identify their associated factors in a sample of hypertensive Middle Eastern patients. METHODS: We previously conducted an observational study between May 2011 and September 2012 to assess antihypertensive treatment adherence and its determinants in a sample of 1,470 hypertensive patients in Lebanon and Jordan. The study consisted of 3 visits: at baseline, 3 months, and 6 months, where BP control, health-related quality of life, and treatment adherence were assessed. This post hoc analysis of data from the ADHERENCE study examined BP control in terms of target attainment at 3 months and 6 months, and target maintenance at 6 months in treatment-eligible patients as well as the determinants of BP control including the impact of the new JNC8 (Eighth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure) guideline on treatment eligibility and target BP attainment in these patients. RESULTS: Based on JNC8 definitions, our results revealed that 81.2% of patients achieved BP control at 6 months. At 3 months, 62.2% achieved BP control; of those, only 57.5% maintained BP control till 6 months. Factors associated with higher BP target attainment at 3 months were higher educational level, new hypertension diagnosis, older age, and lower waist circumference, systolic BP, and diastolic BP at baseline. Factors associated with higher BP target attainment at 6 months were Lebanese nationality, new hypertension diagnosis, absence of chronic kidney disease, lower systolic BP at baseline, reaching BP target at 3 months, and having a BP target of <150/90 mmHg. CONCLUSION: Older age, higher education levels, recent hypertension diagnosis, early achievement of target BP, and having milder disease at baseline were associated with better BP control. Moreover, JNC8 guideline reduced the number of treatment-eligible patients and increased BP target attainment. Dove Medical Press 2019-03-06 /pmc/articles/PMC6410753/ /pubmed/30881006 http://dx.doi.org/10.2147/VHRM.S188981 Text en © 2019 Alhaddad et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Alhaddad, Imad A
Hamoui, Omar
Hammoudeh, Ayman
Mallat, Samir
Blood pressure control in treated hypertensive Middle Eastern patients: a post hoc analysis based on JNC8 definitions
title Blood pressure control in treated hypertensive Middle Eastern patients: a post hoc analysis based on JNC8 definitions
title_full Blood pressure control in treated hypertensive Middle Eastern patients: a post hoc analysis based on JNC8 definitions
title_fullStr Blood pressure control in treated hypertensive Middle Eastern patients: a post hoc analysis based on JNC8 definitions
title_full_unstemmed Blood pressure control in treated hypertensive Middle Eastern patients: a post hoc analysis based on JNC8 definitions
title_short Blood pressure control in treated hypertensive Middle Eastern patients: a post hoc analysis based on JNC8 definitions
title_sort blood pressure control in treated hypertensive middle eastern patients: a post hoc analysis based on jnc8 definitions
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410753/
https://www.ncbi.nlm.nih.gov/pubmed/30881006
http://dx.doi.org/10.2147/VHRM.S188981
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