Cargando…

The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms

SUMOylation (small ubiquitin-like modifier) in the DNA double-strand break (DSB) response regulates recruitment, activity, and clearance of repair factors. However, our understanding of a role for deSUMOylation in this process is limited. Here we identify different mechanistic roles for deSUMOylatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Garvin, Alexander J., Walker, Alexandra K., Densham, Ruth M., Chauhan, Anoop Singh, Stone, Helen R., Mackay, Hannah L., Jamshad, Mohammed, Starowicz, Katarzyna, Daza-Martin, Manuel, Ronson, George E., Lanz, Alexander J., Beesley, James F., Morris, Joanna R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411010/ https://www.ncbi.nlm.nih.gov/pubmed/30796017 http://dx.doi.org/10.1101/gad.321125.118

Ejemplares similares

A Virally Encoded DeSUMOylase Activity Is Required for Cytomegalovirus Reactivation from Latency
por: Poole, Emma L., et al.
Publicado: (2018)

Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway
por: Li, Jianshuang, et al.
Publicado: (2018)

Publisher Correction: Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway
por: Li, Jianshuang, et al.
Publicado: (2018)

PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways
por: Beck, Carole, et al.
Publicado: (2014)

LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining
por: Lawrence, Katherine S., et al.
Publicado: (2016)

Measuring nonhomologous end-joining, homologous recombination and alternative end-joining simultaneously at an endogenous locus in any transfectable human cell
por: Hussain, Suleman S, et al.
Publicado: (2021)

Nonhomologous DNA End Joining in Cell-Free Extracts
por: Sharma, Sheetal, et al.
Publicado: (2010)

The Minimal Bacillus subtilis Nonhomologous End Joining Repair Machinery
por: de Vega, Miguel
Publicado: (2013)

Evolutionary and Comparative Analysis of Bacterial Nonhomologous End Joining Repair
por: Sharda, Mohak, et al.
Publicado: (2020)

A noncatalytic function of the ligation complex during nonhomologous end joining
por: Cottarel, Jessica, et al.
Publicado: (2013)

Cooperative Assembly of a Protein-DNA Filament for Nonhomologous End Joining
por: Tsai, Chun J., et al.
Publicado: (2013)

Reconstitution of Mycobacterium marinum Nonhomologous DNA End Joining Pathway in Leishmania
por: Zhang, Wen-Wei, et al.
Publicado: (2022)

Involvement of Artemis in nonhomologous end-joining during immunoglobulin class switch recombination
por: Du, Likun, et al.
Publicado: (2008)

Positive selection on the nonhomologous end-joining factor Cernunnos-XLF in the human lineage
por: Pavlicek, Adam, et al.
Publicado: (2006)

Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11
por: Di Virgilio, Michela, et al.
Publicado: (2005)

Coincident In Vitro Analysis of DNA-PK-Dependent and -Independent Nonhomologous End Joining
por: Hendrickson, Cynthia L., et al.
Publicado: (2010)

Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?
por: Strande, Natasha Tiffany, et al.
Publicado: (2012)

Hyperactivation of PARP Triggers Nonhomologous End-Joining in Repair-Deficient Mouse Fibroblasts
por: Gassman, Natalie R., et al.
Publicado: (2012)

Efficient processing of abasic sites by bacterial nonhomologous end-joining Ku proteins
por: de Ory, Ana, et al.
Publicado: (2014)

Smarcal1 promotes double-strand-break repair by nonhomologous end-joining
por: Keka, Islam Shamima, et al.
Publicado: (2015)

A Process of Resection-Dependent Nonhomologous End Joining Involving the Goddess Artemis
por: Löbrich, Markus, et al.
Publicado: (2017)

Causes and Effects of Loss of Classical Nonhomologous End Joining Pathway in Parasitic Eukaryotes
por: Nenarokova, Anna, et al.
Publicado: (2019)

DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys?
por: Weterings, Eric, et al.
Publicado: (2007)

PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks
por: Couto, C. Anne-Marie, et al.
Publicado: (2011)

Structural Biology of DNA Repair: Spatial Organisation of the Multicomponent Complexes of Nonhomologous End Joining
por: Ochi, Takashi, et al.
Publicado: (2010)

The fidelity of the ligation step determines how ends are resolved during Nonhomologous end joining
por: Waters, Crystal A., et al.
Publicado: (2014)

XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in Igh genes
por: Saribasak, Huseyin, et al.
Publicado: (2011)

ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells
por: Adams, Bret R., et al.
Publicado: (2010)

DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation
por: Simsek, Deniz, et al.
Publicado: (2011)

BRCA2 antagonizes classical and alternative nonhomologous end-joining to prevent gross genomic instability
por: Han, Jinhua, et al.
Publicado: (2017)

A CRISPR-Assisted Nonhomologous End-Joining Strategy for Efficient Genome Editing in Mycobacterium tuberculosis
por: Yan, Mei-Yi, et al.
Publicado: (2020)

Inhibition of nonhomologous end joining‐mediated DNA repair enhances anti‐HBV CRISPR therapy
por: Murai, Kazuhiro, et al.
Publicado: (2022)

TDP1 suppresses mis-joining of radiomimetic DNA double-strand breaks and cooperates with Artemis to promote optimal nonhomologous end joining
por: Kawale, Ajinkya S, et al.
Publicado: (2018)

End-bridging is required for pol μ to efficiently promote repair of noncomplementary ends by nonhomologous end joining
por: Davis, Bryan J., et al.
Publicado: (2008)

Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV–deficient B cells
por: Han, Li, et al.
Publicado: (2008)

Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV–deficient B cells
por: Han, Li, et al.
Publicado: (2008)

The Role of ATM in the Deficiency in Nonhomologous End-Joining near Telomeres in a Human Cancer Cell Line
por: Muraki, Keiko, et al.
Publicado: (2013)

TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer
por: Banerjee, Rajat, et al.
Publicado: (2014)

CRISPR/Cas9-Induced Double-Strand Break Repair in Arabidopsis Nonhomologous End-Joining Mutants
por: Shen, Hexi, et al.
Publicado: (2016)

POT1 inhibits the efficiency but promotes the fidelity of nonhomologous end joining at non-telomeric DNA regions
por: Yu, Yang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_02bi3migepd0c5roc9c61vic1j