Molecular Biomarkers and Histological Parameters Impact on Survival and Response to First- Line Systemic Therapy of Metastatic Colorectal Cancer Patients

BACKGROUND: Histological parameters of primary tumour and nodal metastases are prognostic factors for survival of operable colorectal (CRC) patients, but not predictive for response rate of systemic therapy. KRAS mutations in codons 12 and 13 were first recognized as a predictive factor for resistan...

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Detalles Bibliográficos
Autores principales: Rebersek, Martina, Mesti, Tanja, Boc, Marko, Ocvirk, Janja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411021/
https://www.ncbi.nlm.nih.gov/pubmed/30840593
http://dx.doi.org/10.2478/raon-2019-0013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411021/
https://www.ncbi.nlm.nih.gov/pubmed/30840593
http://dx.doi.org/10.2478/raon-2019-0013

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