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Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells

Plasmodium parasites invade and multiply inside red blood cells (RBC). Through a cycle of maturation, asexual replication, rupture and release of multiple infective merozoites, parasitised RBC (pRBC) can reach very high numbers in vivo, a process that correlates with disease severity in humans and e...

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Detalles Bibliográficos
Autores principales: Akter, Jasmin, Khoury, David S., Aogo, Rosemary, Lansink, Lianne I. M., SheelaNair, Arya, Thomas, Bryce S., Laohamonthonkul, Pawat, Pernold, Clara P. S., Dixon, Matthew W. A., Soon, Megan S. F., Fogg, Lily G., Engel, Jessica A., Elliott, Trish, Sebina, Ismail, James, Kylie R., Cromer, Deborah, Davenport, Miles P., Haque, Ashraful
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411214/
https://www.ncbi.nlm.nih.gov/pubmed/30811498
http://dx.doi.org/10.1371/journal.ppat.1007599