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Activation-induced deaminase (AID) localizes to the nucleus in brief pulses
Activation-induced deaminase (AID) converts C to U and 5-methyl-C to T. These mutagenic activities are critical to immunoglobulin (Ig) gene diversification and epigenetic reprogramming, but they must be tightly controlled to prevent compromising cell fitness. AID acts in the nucleus but localizes pr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411215/ https://www.ncbi.nlm.nih.gov/pubmed/30811383 http://dx.doi.org/10.1371/journal.pgen.1007968 |