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Liver Transplantation for Recurrent Cholangitis From Von Meyenburg Complexes

Von Meyenburg complexes, or multiple biliary hamartomas, are often asymptomatic lesions incidentally discovered during abdominal or hepatic imaging. The presentation of clinically significant Von Meyenburg complexes ranges from cholestasis and self-limited episodes of cholangitis to malignant degene...

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Detalles Bibliográficos
Autores principales: Panda, Nikhil, Brackett, Diane, Eymard, Corey, Kawai, Tatsuo, Markmann, James, Kotton, Camille N., Andersson, Karin, Yeh, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411223/
https://www.ncbi.nlm.nih.gov/pubmed/30882033
http://dx.doi.org/10.1097/TXD.0000000000000867
Descripción
Sumario:Von Meyenburg complexes, or multiple biliary hamartomas, are often asymptomatic lesions incidentally discovered during abdominal or hepatic imaging. The presentation of clinically significant Von Meyenburg complexes ranges from cholestasis and self-limited episodes of cholangitis to malignant degeneration into cholangiocarcinoma. In cases of persistent or recurrent cholangitis, treatment is a significant challenge. Definitive source control with liver transplantation, as in other cases of cholestatic liver disease, may be necessary.