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Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection

The phenotypic characterization of the cells in which HIV persists during antiretroviral therapy (ART) remains technically challenging. We developed a simple flow cytometry-based assay to quantify and characterize infected cells producing HIV proteins during untreated and treated HIV infection. By c...

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Detalles Bibliográficos
Autores principales: Pardons, Marion, Baxter, Amy E., Massanella, Marta, Pagliuzza, Amélie, Fromentin, Rémi, Dufour, Caroline, Leyre, Louise, Routy, Jean-Pierre, Kaufmann, Daniel E., Chomont, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411230/
https://www.ncbi.nlm.nih.gov/pubmed/30811499
http://dx.doi.org/10.1371/journal.ppat.1007619