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An Unusual Case of Essential Tremor Deep Brain Stimulation: Where is the Lead?

CLINICAL VIGNETTE: A 73‐year‐old female with essential tremor (ET) underwent bilateral thalamic ventralis intermedius (Vim) deep brain stimulation (DBS) surgery. The leads provided tremor benefit, but the location was suboptimal and contributed to stimulation‐induced hemichorea. CLINICAL DILEMMA: Ca...

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Autores principales: Spears, C. Chauncey, Almeida, Leonardo, Okun, Michael S., Deeb, Wissam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Columbia University Libraries/Information Services 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411417/
https://www.ncbi.nlm.nih.gov/pubmed/30867977
http://dx.doi.org/10.7916/d8-xj6w-cm53
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author Spears, C. Chauncey
Almeida, Leonardo
Okun, Michael S.
Deeb, Wissam
author_facet Spears, C. Chauncey
Almeida, Leonardo
Okun, Michael S.
Deeb, Wissam
author_sort Spears, C. Chauncey
collection PubMed
description CLINICAL VIGNETTE: A 73‐year‐old female with essential tremor (ET) underwent bilateral thalamic ventralis intermedius (Vim) deep brain stimulation (DBS) surgery. The leads provided tremor benefit, but the location was suboptimal and contributed to stimulation‐induced hemichorea. CLINICAL DILEMMA: Can patients with ET derive benefit when stimulating outside the Vim? What do we know about stimulation‐induced hemichorea in the setting of ET? CLINICAL SOLUTION: Lead localization combined with advanced programming strategies can be employed to troubleshoot DBS in settings when benefits are observed along with adverse effects. GAP IN KNOWLEDGE: Sparse information exists about DBS when applied to neuroanatomic regions outside the Vim for the management of ET. Subthalamic nucleus DBS‐induced chorea has been reported in multiple movement disorders, but not in ET.
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spelling pubmed-64114172019-03-13 An Unusual Case of Essential Tremor Deep Brain Stimulation: Where is the Lead? Spears, C. Chauncey Almeida, Leonardo Okun, Michael S. Deeb, Wissam Tremor Other Hyperkinet Mov (N Y) Deep Brain Stimulation Case Files CLINICAL VIGNETTE: A 73‐year‐old female with essential tremor (ET) underwent bilateral thalamic ventralis intermedius (Vim) deep brain stimulation (DBS) surgery. The leads provided tremor benefit, but the location was suboptimal and contributed to stimulation‐induced hemichorea. CLINICAL DILEMMA: Can patients with ET derive benefit when stimulating outside the Vim? What do we know about stimulation‐induced hemichorea in the setting of ET? CLINICAL SOLUTION: Lead localization combined with advanced programming strategies can be employed to troubleshoot DBS in settings when benefits are observed along with adverse effects. GAP IN KNOWLEDGE: Sparse information exists about DBS when applied to neuroanatomic regions outside the Vim for the management of ET. Subthalamic nucleus DBS‐induced chorea has been reported in multiple movement disorders, but not in ET. Columbia University Libraries/Information Services 2019-03-07 /pmc/articles/PMC6411417/ /pubmed/30867977 http://dx.doi.org/10.7916/d8-xj6w-cm53 Text en © 2019 Spears et al. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution–Noncommercial–No Derivatives License, which permits the user to copy, distribute, and transmit the work provided that the original authors and source are credited; that no commercial use is made of the work; and that the work is not altered or transformed.
spellingShingle Deep Brain Stimulation Case Files
Spears, C. Chauncey
Almeida, Leonardo
Okun, Michael S.
Deeb, Wissam
An Unusual Case of Essential Tremor Deep Brain Stimulation: Where is the Lead?
title An Unusual Case of Essential Tremor Deep Brain Stimulation: Where is the Lead?
title_full An Unusual Case of Essential Tremor Deep Brain Stimulation: Where is the Lead?
title_fullStr An Unusual Case of Essential Tremor Deep Brain Stimulation: Where is the Lead?
title_full_unstemmed An Unusual Case of Essential Tremor Deep Brain Stimulation: Where is the Lead?
title_short An Unusual Case of Essential Tremor Deep Brain Stimulation: Where is the Lead?
title_sort unusual case of essential tremor deep brain stimulation: where is the lead?
topic Deep Brain Stimulation Case Files
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411417/
https://www.ncbi.nlm.nih.gov/pubmed/30867977
http://dx.doi.org/10.7916/d8-xj6w-cm53
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