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Pak1 Kinase Promotes Activated T Cell Trafficking by Regulating the Expression of L-Selectin and CCR7

Normal function of the adaptive immune system requires trafficking of T cells between the blood and lymphoid organs. Lymphocyte homing to lymph nodes requires that they cross endothelial barriers present in blood vessels and lymphatics. This multi-step process requires a remodeling of the lymphocyte...

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Detalles Bibliográficos
Autores principales:	Dios-Esponera, Ana, Melis, Nicolas, Subramanian, Bhagawat C., Weigert, Roberto, Samelson, Lawrence E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411651/ https://www.ncbi.nlm.nih.gov/pubmed/30891040 http://dx.doi.org/10.3389/fimmu.2019.00370

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