Computational analysis of the evolutionarily conserved Missing In Metastasis/Metastasis Suppressor 1 gene predicts novel interactions, regulatory regions and transcriptional control

Missing in Metastasis (MIM), or Metastasis Suppressor 1 (MTSS1), is a highly conserved protein, which links the plasma membrane to the actin cytoskeleton. MIM has been implicated in various cancers, however, its modes of action remain largely enigmatic. Here, we performed an extensive in silico char...

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Detalles Bibliográficos
Autores principales: Petrov, Petar, Sarapulov, Alexey V., Eöry, Lel, Scielzo, Cristina, Scarfò, Lydia, Smith, Jacqueline, Burt, David W., Mattila, Pieta K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411742/
https://www.ncbi.nlm.nih.gov/pubmed/30858428
http://dx.doi.org/10.1038/s41598-019-40697-1

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