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Deletion of D-Lactate Dehydrogenase A in Neisseria meningitidis Promotes Biofilm Formation Through Increased Autolysis and Extracellular DNA Release

Neisseria meningitidis is a Gram-negative bacterium that asymptomatically colonizes the human nasopharyngeal mucosa. Pilus-mediated initial adherence of N. meningitidis to the epithelial mucosa is followed by the formation of three-dimensional aggregates, called microcolonies. Dispersal from microco...

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Detalles Bibliográficos
Autores principales: Sigurlásdóttir, Sara, Wassing, Gabriela M., Zuo, Fanglei, Arts, Melanie, Jonsson, Ann-Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411758/
https://www.ncbi.nlm.nih.gov/pubmed/30891026
http://dx.doi.org/10.3389/fmicb.2019.00422