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IGF1 Gene Therapy Modifies Microglia in the Striatum of Senile Rats

Microglial cells become dystrophic with aging; this phenotypic alteration contributes to basal central nervous system (CNS) neuroinflammation being a risk factor for age related neurodegenerative diseases. In previous studies we have observed that insulin like growth factor 1 (IGF1) gene therapy is...

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Detalles Bibliográficos
Autores principales:	Falomir-Lockhart, Eugenia, Dolcetti, Franco Juan Cruz, García-Segura, Luis Miguel, Hereñú, Claudia Beatriz, Bellini, Maria Jose
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411822/ https://www.ncbi.nlm.nih.gov/pubmed/30890930 http://dx.doi.org/10.3389/fnagi.2019.00048

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