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Cargo diffusion shortens single-kinesin runs at low viscous drag
Molecular motors such as kinesin-1 drive active, long-range transport of cargos along microtubules in cells. Thermal diffusion of the cargo can impose a randomly directed, fluctuating mechanical load on the motor carrying the cargo. Recent experiments highlighted a strong asymmetry in the sensitivit...
Autores principales: | Wilson, John O., Quint, David A., Gopinathan, Ajay, Xu, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411862/ https://www.ncbi.nlm.nih.gov/pubmed/30858425 http://dx.doi.org/10.1038/s41598-019-40550-5 |
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