Low-dose 2-deoxyglucose and metformin synergically inhibit proliferation of human polycystic kidney cells by modulating glucose metabolism

Polycystic kidney disease (PKD) is a common hereditary kidney disease with abnormal proliferation and apoptosis of kidney cystic epithelial cells, eventually leading to chronic renal failure. Currently, there are no effective treatment methods. Similar to tumor cells, cystic epithelial cells have ab...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Ma, Yuxiang, Zhang, Yingjie, Fu, Bo, Wu, Xiaoyuan, Li, Qinggang, Cai, Guangyan, Chen, Xiangmei, Bai, Xue-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411866/
https://www.ncbi.nlm.nih.gov/pubmed/30886744
http://dx.doi.org/10.1038/s41420-019-0156-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411866/
https://www.ncbi.nlm.nih.gov/pubmed/30886744
http://dx.doi.org/10.1038/s41420-019-0156-8

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