p53 β-hydroxybutyrylation attenuates p53 activity

p53 is an essential tumor suppressor, whose activity is finely tuned by the posttranslational modifications. Previous research has reported that β-hydroxybutyrate (BHB) induces β-hydroxybutyrylation (Kbhb), which is a novel histone posttranslational modification. Here we report that p53 is modified...

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Detalles Bibliográficos
Autores principales: Liu, Kun, Li, Fangzhou, Sun, Qianqian, Lin, Ning, Han, Haichao, You, Kaiqiang, Tian, Feng, Mao, Zebin, Li, Tingting, Tong, Tanjun, Geng, Meiyu, Zhao, Yingming, Gu, Wei, Zhao, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411878/
https://www.ncbi.nlm.nih.gov/pubmed/30858356
http://dx.doi.org/10.1038/s41419-019-1463-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411878/
https://www.ncbi.nlm.nih.gov/pubmed/30858356
http://dx.doi.org/10.1038/s41419-019-1463-y

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