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The In Vitro Biotransformation of the Fusion Protein Tetranectin-Apolipoprotein A1

As more and more protein biotherapeutics enter the drug discovery pipelines, there is an increasing interest in tools for mechanistic drug metabolism investigations of biologics in order to identify and prioritize the most promising candidates. Understanding or even predicting the in vivo clearance...

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Detalles Bibliográficos
Autores principales: Schadt, Simone, Husser, Christophe, Staack, Roland F., Ekiciler, Aynur, Qiu, Na Hong, Fowler, Stephen, Funk, Christoph, Kratochwil, Nicole A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411889/
https://www.ncbi.nlm.nih.gov/pubmed/30858459
http://dx.doi.org/10.1038/s41598-019-40542-5