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The In Vitro Biotransformation of the Fusion Protein Tetranectin-Apolipoprotein A1
As more and more protein biotherapeutics enter the drug discovery pipelines, there is an increasing interest in tools for mechanistic drug metabolism investigations of biologics in order to identify and prioritize the most promising candidates. Understanding or even predicting the in vivo clearance...
Autores principales: | Schadt, Simone, Husser, Christophe, Staack, Roland F., Ekiciler, Aynur, Qiu, Na Hong, Fowler, Stephen, Funk, Christoph, Kratochwil, Nicole A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411889/ https://www.ncbi.nlm.nih.gov/pubmed/30858459 http://dx.doi.org/10.1038/s41598-019-40542-5 |
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