Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease

BACKGROUND & AIMS: Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are emerging as leading causes of liver disease worldwide. Currently, no specific pharmacologic therapy is available for NAFLD/NASH, which has been recognized as one of the major unmet medical nee...

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Detalles Bibliográficos
Autores principales: Cansby, Emmelie, Nuñez-Durán, Esther, Magnusson, Elin, Amrutkar, Manoj, Booten, Sheri L., Kulkarni, Nagaraj M., Svensson, L. Thomas, Borén, Jan, Marschall, Hanns-Ulrich, Aghajan, Mariam, Mahlapuu, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411916/
https://www.ncbi.nlm.nih.gov/pubmed/30576769
http://dx.doi.org/10.1016/j.jcmgh.2018.12.004

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