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H-NS uses an autoinhibitory conformational switch for environment-controlled gene silencing
As an environment-dependent pleiotropic gene regulator in Gram-negative bacteria, the H-NS protein is crucial for adaptation and toxicity control of human pathogens such as Salmonella, Vibrio cholerae or enterohaemorrhagic Escherichia coli. Changes in temperature affect the capacity of H-NS to form...
Autores principales: | Shahul Hameed, Umar F, Liao, Chenyi, Radhakrishnan, Anand K, Huser, Franceline, Aljedani, Safia S, Zhao, Xiaochuan, Momin, Afaque A, Melo, Fernando A, Guo, Xianrong, Brooks, Claire, Li, Yu, Cui, Xuefeng, Gao, Xin, Ladbury, John E, Jaremko, Łukasz, Jaremko, Mariusz, Li, Jianing, Arold, Stefan T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411929/ https://www.ncbi.nlm.nih.gov/pubmed/30597093 http://dx.doi.org/10.1093/nar/gky1299 |
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