Isolation and genome-wide characterization of cellular DNA:RNA triplex structures

RNA can directly bind to purine-rich DNA via Hoogsteen base pairing, forming a DNA:RNA triple helical structure that anchors the RNA to specific sequences and allows guiding of transcription regulators to distinct genomic loci. To unravel the prevalence of DNA:RNA triplexes in living cells, we have...

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Detalles Bibliográficos
Autores principales: Sentürk Cetin, Nevcin, Kuo, Chao-Chung, Ribarska, Teodora, Li, Ronghui, Costa, Ivan G, Grummt, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411930/
https://www.ncbi.nlm.nih.gov/pubmed/30605520
http://dx.doi.org/10.1093/nar/gky1305

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