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Bias-minimized quantification of microRNA reveals widespread alternative processing and 3′ end modification

MicroRNAs (miRNAs) modulate diverse biological and pathological processes via post-transcriptional gene silencing. High-throughput small RNA sequencing (sRNA-seq) has been widely adopted to investigate the functions and regulatory mechanisms of miRNAs. However, accurate quantification of miRNAs has...

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Detalles Bibliográficos
Autores principales: Kim, Haedong, Kim, Jimi, Kim, Kijun, Chang, Hyeshik, You, Kwontae, Kim, V Narry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411932/
https://www.ncbi.nlm.nih.gov/pubmed/30605524
http://dx.doi.org/10.1093/nar/gky1293

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