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SQuIRE reveals locus-specific regulation of interspersed repeat expression

Transposable elements (TEs) are interspersed repeat sequences that make up much of the human genome. Their expression has been implicated in development and disease. However, TE-derived RNA-seq reads are difficult to quantify. Past approaches have excluded these reads or aggregated RNA expression to...

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Detalles Bibliográficos
Autores principales: Yang, Wan R, Ardeljan, Daniel, Pacyna, Clarissa N, Payer, Lindsay M, Burns, Kathleen H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411935/
https://www.ncbi.nlm.nih.gov/pubmed/30624635
http://dx.doi.org/10.1093/nar/gky1301