Cargando…

Low Electric Treatment activates Rho GTPase via Heat Shock Protein 90 and Protein Kinase C for Intracellular Delivery of siRNA

Low electric treatment (LET) promotes intracellular delivery of naked siRNA by altering cellular physiology. However, which signaling molecules and cellular events contribute to LET-mediated siRNA uptake are unclear. Here, we used isobaric tags in relative and absolute quantification (iTRAQ) proteom...

Descripción completa

Detalles Bibliográficos
Autores principales: Hasan, Mahadi, Hama, Susumu, Kogure, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412017/
https://www.ncbi.nlm.nih.gov/pubmed/30858501
http://dx.doi.org/10.1038/s41598-019-40904-z