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Over 2000-Fold Increased Production of the Leaderless Bacteriocin Garvicin KS by Increasing Gene Dose and Optimization of Culture Conditions

The leaderless bacteriocin Garvicin KS (GarKS) is a potent antimicrobial, being active against a wide range of important pathogens. GarKS production by the native producer Lactococcus garvieae KS1546 is, however, relatively low (80 BU/ml) under standard laboratory growth conditions (batch culture in...

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Detalles Bibliográficos
Autores principales:	Telke, Amar A., Ovchinnikov, Kirill V., Vuoristo, Kiira S., Mathiesen, Geir, Thorstensen, Tage, Diep, Dzung B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412029/ https://www.ncbi.nlm.nih.gov/pubmed/30891018 http://dx.doi.org/10.3389/fmicb.2019.00389

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