Preclinical study using androgen receptor (AR) degradation enhancer to increase radiotherapy efficacy via targeting radiation-increased AR to better suppress prostate cancer progression

BACKGROUND: While androgen deprivation therapy (ADT) and radiotherapy (RT) are currently used together to treat locally advanced prostate cancer (PCa), RT might have the adverse effect of increasing the PCa androgen receptor (AR) protein expression, which might then increase the resistance to contin...

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Detalles Bibliográficos
Autores principales: Chou, Fu-Ju, Chen, Yuhchyau, Chen, Dong, Niu, Yuanjie, Li, Gonghui, Keng, Peter, Yeh, Shuyuan, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412086/
https://www.ncbi.nlm.nih.gov/pubmed/30692044
http://dx.doi.org/10.1016/j.ebiom.2018.12.050

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