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Regulation of Rep helicase unwinding by an auto-inhibitory subdomain

Helicases are biomolecular motors that unwind nucleic acids, and their regulation is essential for proper maintenance of genomic integrity. Escherichia coli Rep helicase, whose primary role is to help restart stalled replication, serves as a model for Superfamily I helicases. The activity of Rep-lik...

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Detalles Bibliográficos
Autores principales:	Makurath, Monika A, Whitley, Kevin D, Nguyen, Binh, Lohman, Timothy M, Chemla, Yann R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412110/ https://www.ncbi.nlm.nih.gov/pubmed/30690484 http://dx.doi.org/10.1093/nar/gkz023

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