Determining the effects of DNA sequence on Hel308 helicase translocation along single-stranded DNA using nanopore tweezers

Motor enzymes that process nucleic-acid substrates play vital roles in all aspects of genome replication, expression, and repair. The DNA and RNA nucleobases are known to affect the kinetics of these systems in biologically meaningful ways. Recently, it was shown that DNA bases control the transloca...

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Detalles Bibliográficos
Autores principales: Craig, Jonathan M, Laszlo, Andrew H, Nova, Ian C, Brinkerhoff, Henry, Noakes, Matthew T, Baker, Katherine S, Bowman, Jasmine L, Higinbotham, Hugh R, Mount, Jonathan W, Gundlach, Jens H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412116/
https://www.ncbi.nlm.nih.gov/pubmed/30649515
http://dx.doi.org/10.1093/nar/gkz004

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