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Matching tRNA modifications in humans to their known and predicted enzymes
tRNA are post-transcriptionally modified by chemical modifications that affect all aspects of tRNA biology. An increasing number of mutations underlying human genetic diseases map to genes encoding for tRNA modification enzymes. However, our knowledge on human tRNA-modification genes remains fragmen...
Autores principales: | de Crécy-Lagard, Valérie, Boccaletto, Pietro, Mangleburg, Carl G, Sharma, Puneet, Lowe, Todd M, Leidel, Sebastian A, Bujnicki, Janusz M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412123/ https://www.ncbi.nlm.nih.gov/pubmed/30698754 http://dx.doi.org/10.1093/nar/gkz011 |
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