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Matching tRNA modifications in humans to their known and predicted enzymes

tRNA are post-transcriptionally modified by chemical modifications that affect all aspects of tRNA biology. An increasing number of mutations underlying human genetic diseases map to genes encoding for tRNA modification enzymes. However, our knowledge on human tRNA-modification genes remains fragmen...

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Detalles Bibliográficos
Autores principales: de Crécy-Lagard, Valérie, Boccaletto, Pietro, Mangleburg, Carl G, Sharma, Puneet, Lowe, Todd M, Leidel, Sebastian A, Bujnicki, Janusz M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412123/
https://www.ncbi.nlm.nih.gov/pubmed/30698754
http://dx.doi.org/10.1093/nar/gkz011

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