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Selection of self-priming molecular replicators
Self-priming amplification of oligonucleotides is possible based on foldback of 3′ ends, self-priming, and concatemerization, especially in the presence of phosphorothioate linkages. Such a simple replicative mechanism may have led to the accumulation of specific replicators at or near the origin of...
Autores principales: | Park, Daechan, Ellington, Andrew D, Jung, Cheulhee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412129/ https://www.ncbi.nlm.nih.gov/pubmed/30698805 http://dx.doi.org/10.1093/nar/gkz044 |
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