Codon stabilization coefficient as a metric to gain insights into mRNA stability and codon bias and their relationships with translation

The codon stabilization coefficient (CSC) is derived from the correlation between each codon frequency in transcripts and mRNA half-life experimental data. In this work, we used this metric as a reference to compare previously published Saccharomyces cerevisiae mRNA half-life datasets and investigat...

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Detalles Bibliográficos
Autores principales: Carneiro, Rodolfo L, Requião, Rodrigo D, Rossetto, Silvana, Domitrovic, Tatiana, Palhano, Fernando L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412131/
https://www.ncbi.nlm.nih.gov/pubmed/30698781
http://dx.doi.org/10.1093/nar/gkz033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412131/
https://www.ncbi.nlm.nih.gov/pubmed/30698781
http://dx.doi.org/10.1093/nar/gkz033

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