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The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source
The Macromolecular Femtosecond Crystallography (MFX) instrument at the Linac Coherent Light Source (LCLS) is the seventh and newest instrument at the world’s first hard X-ray free-electron laser. It was designed with a primary focus on structural biology, employing the ultrafast pulses of X-rays fro...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412173/ https://www.ncbi.nlm.nih.gov/pubmed/30855242 http://dx.doi.org/10.1107/S1600577519001577 |
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| author | Sierra, Raymond G. Batyuk, Alexander Sun, Zhibin Aquila, Andrew Hunter, Mark S. Lane, Thomas J. Liang, Mengning Yoon, Chun Hong Alonso-Mori, Roberto Armenta, Rebecca Castagna, Jean-Charles Hollenbeck, Michael Osier, Ted O. Hayes, Matt Aldrich, Jeff Curtis, Robin Koglin, Jason E. Rendahl, Theodore Rodriguez, Evan Carbajo, Sergio Guillet, Serge Paul, Rob Hart, Philip Nakahara, Kazutaka Carini, Gabriella DeMirci, Hasan Dao, E. Han Hayes, Brandon M. Rao, Yashas P. Chollet, Matthieu Feng, Yiping Fuller, Franklin D. Kupitz, Christopher Sato, Takahiro Seaberg, Matthew H. Song, Sanghoon van Driel, Tim B. Yavas, Hasan Zhu, Diling Cohen, Aina E. Wakatsuki, Soichi Boutet, Sébastien |
| author_facet | Sierra, Raymond G. Batyuk, Alexander Sun, Zhibin Aquila, Andrew Hunter, Mark S. Lane, Thomas J. Liang, Mengning Yoon, Chun Hong Alonso-Mori, Roberto Armenta, Rebecca Castagna, Jean-Charles Hollenbeck, Michael Osier, Ted O. Hayes, Matt Aldrich, Jeff Curtis, Robin Koglin, Jason E. Rendahl, Theodore Rodriguez, Evan Carbajo, Sergio Guillet, Serge Paul, Rob Hart, Philip Nakahara, Kazutaka Carini, Gabriella DeMirci, Hasan Dao, E. Han Hayes, Brandon M. Rao, Yashas P. Chollet, Matthieu Feng, Yiping Fuller, Franklin D. Kupitz, Christopher Sato, Takahiro Seaberg, Matthew H. Song, Sanghoon van Driel, Tim B. Yavas, Hasan Zhu, Diling Cohen, Aina E. Wakatsuki, Soichi Boutet, Sébastien |
| author_sort | Sierra, Raymond G. |
| collection | PubMed |
| description | The Macromolecular Femtosecond Crystallography (MFX) instrument at the Linac Coherent Light Source (LCLS) is the seventh and newest instrument at the world’s first hard X-ray free-electron laser. It was designed with a primary focus on structural biology, employing the ultrafast pulses of X-rays from LCLS at atmospheric conditions to overcome radiation damage limitations in biological measurements. It is also capable of performing various time-resolved measurements. The MFX design consists of a versatile base system capable of supporting multiple methods, techniques and experimental endstations. The primary techniques supported are forward scattering and crystallography, with capabilities for various spectroscopic methods and time-resolved measurements. The location of the MFX instrument allows for utilization of multiplexing methods, increasing user access to LCLS by running multiple experiments simultaneously. |
| format | Online Article Text |
| id | pubmed-6412173 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-64121732019-04-04 The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source Sierra, Raymond G. Batyuk, Alexander Sun, Zhibin Aquila, Andrew Hunter, Mark S. Lane, Thomas J. Liang, Mengning Yoon, Chun Hong Alonso-Mori, Roberto Armenta, Rebecca Castagna, Jean-Charles Hollenbeck, Michael Osier, Ted O. Hayes, Matt Aldrich, Jeff Curtis, Robin Koglin, Jason E. Rendahl, Theodore Rodriguez, Evan Carbajo, Sergio Guillet, Serge Paul, Rob Hart, Philip Nakahara, Kazutaka Carini, Gabriella DeMirci, Hasan Dao, E. Han Hayes, Brandon M. Rao, Yashas P. Chollet, Matthieu Feng, Yiping Fuller, Franklin D. Kupitz, Christopher Sato, Takahiro Seaberg, Matthew H. Song, Sanghoon van Driel, Tim B. Yavas, Hasan Zhu, Diling Cohen, Aina E. Wakatsuki, Soichi Boutet, Sébastien J Synchrotron Radiat Research Papers The Macromolecular Femtosecond Crystallography (MFX) instrument at the Linac Coherent Light Source (LCLS) is the seventh and newest instrument at the world’s first hard X-ray free-electron laser. It was designed with a primary focus on structural biology, employing the ultrafast pulses of X-rays from LCLS at atmospheric conditions to overcome radiation damage limitations in biological measurements. It is also capable of performing various time-resolved measurements. The MFX design consists of a versatile base system capable of supporting multiple methods, techniques and experimental endstations. The primary techniques supported are forward scattering and crystallography, with capabilities for various spectroscopic methods and time-resolved measurements. The location of the MFX instrument allows for utilization of multiplexing methods, increasing user access to LCLS by running multiple experiments simultaneously. International Union of Crystallography 2019-02-22 /pmc/articles/PMC6412173/ /pubmed/30855242 http://dx.doi.org/10.1107/S1600577519001577 Text en © Raymond G. Sierra et al. 2019 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.http://creativecommons.org/licenses/by/2.0/uk/ |
| spellingShingle | Research Papers Sierra, Raymond G. Batyuk, Alexander Sun, Zhibin Aquila, Andrew Hunter, Mark S. Lane, Thomas J. Liang, Mengning Yoon, Chun Hong Alonso-Mori, Roberto Armenta, Rebecca Castagna, Jean-Charles Hollenbeck, Michael Osier, Ted O. Hayes, Matt Aldrich, Jeff Curtis, Robin Koglin, Jason E. Rendahl, Theodore Rodriguez, Evan Carbajo, Sergio Guillet, Serge Paul, Rob Hart, Philip Nakahara, Kazutaka Carini, Gabriella DeMirci, Hasan Dao, E. Han Hayes, Brandon M. Rao, Yashas P. Chollet, Matthieu Feng, Yiping Fuller, Franklin D. Kupitz, Christopher Sato, Takahiro Seaberg, Matthew H. Song, Sanghoon van Driel, Tim B. Yavas, Hasan Zhu, Diling Cohen, Aina E. Wakatsuki, Soichi Boutet, Sébastien The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source |
| title | The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source
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| title_full | The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source
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| title_fullStr | The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source
|
| title_full_unstemmed | The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source
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| title_short | The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source
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| title_sort | macromolecular femtosecond crystallography instrument at the linac coherent light source |
| topic | Research Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412173/ https://www.ncbi.nlm.nih.gov/pubmed/30855242 http://dx.doi.org/10.1107/S1600577519001577 |
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