A versatile liquid-jet setup for the European XFEL

The SPB/SFX instrument of the European XFEL provides unique possibilities for high-throughput serial femtosecond crystallography. This publication presents the liquid-jet sample delivery setup of this instrument. The setup is compatible with state-of-the-art gas dynamic virtual nozzle systems as wel...

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Detalles Bibliográficos
Autores principales: Schulz, J., Bielecki, J., Doak, R. B., Dörner, K., Graceffa, R., Shoeman, R. L., Sikorski, M., Thute, P., Westphal, D., Mancuso, A. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412181/
https://www.ncbi.nlm.nih.gov/pubmed/30855241
http://dx.doi.org/10.1107/S1600577519000894
Descripción
Sumario:The SPB/SFX instrument of the European XFEL provides unique possibilities for high-throughput serial femtosecond crystallography. This publication presents the liquid-jet sample delivery setup of this instrument. The setup is compatible with state-of-the-art gas dynamic virtual nozzle systems as well as high-viscosity extruders and provides space and flexibility for other liquid injection devices and future upgrades. The liquid jets are confined in a differentially pumped catcher assembly and can be replaced within a couple of minutes through a load-lock. A two-microscope imaging system allows visual control of the jets from two perspectives.

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