A versatile liquid-jet setup for the European XFEL

The SPB/SFX instrument of the European XFEL provides unique possibilities for high-throughput serial femtosecond crystallography. This publication presents the liquid-jet sample delivery setup of this instrument. The setup is compatible with state-of-the-art gas dynamic virtual nozzle systems as wel...

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Detalles Bibliográficos
Autores principales: Schulz, J., Bielecki, J., Doak, R. B., Dörner, K., Graceffa, R., Shoeman, R. L., Sikorski, M., Thute, P., Westphal, D., Mancuso, A. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412181/
https://www.ncbi.nlm.nih.gov/pubmed/30855241
http://dx.doi.org/10.1107/S1600577519000894
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author Schulz, J.
Bielecki, J.
Doak, R. B.
Dörner, K.
Graceffa, R.
Shoeman, R. L.
Sikorski, M.
Thute, P.
Westphal, D.
Mancuso, A. P.
author_facet Schulz, J.
Bielecki, J.
Doak, R. B.
Dörner, K.
Graceffa, R.
Shoeman, R. L.
Sikorski, M.
Thute, P.
Westphal, D.
Mancuso, A. P.
author_sort Schulz, J.
collection PubMed
description The SPB/SFX instrument of the European XFEL provides unique possibilities for high-throughput serial femtosecond crystallography. This publication presents the liquid-jet sample delivery setup of this instrument. The setup is compatible with state-of-the-art gas dynamic virtual nozzle systems as well as high-viscosity extruders and provides space and flexibility for other liquid injection devices and future upgrades. The liquid jets are confined in a differentially pumped catcher assembly and can be replaced within a couple of minutes through a load-lock. A two-microscope imaging system allows visual control of the jets from two perspectives.
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spelling pubmed-64121812019-04-04 A versatile liquid-jet setup for the European XFEL Schulz, J. Bielecki, J. Doak, R. B. Dörner, K. Graceffa, R. Shoeman, R. L. Sikorski, M. Thute, P. Westphal, D. Mancuso, A. P. J Synchrotron Radiat Research Papers The SPB/SFX instrument of the European XFEL provides unique possibilities for high-throughput serial femtosecond crystallography. This publication presents the liquid-jet sample delivery setup of this instrument. The setup is compatible with state-of-the-art gas dynamic virtual nozzle systems as well as high-viscosity extruders and provides space and flexibility for other liquid injection devices and future upgrades. The liquid jets are confined in a differentially pumped catcher assembly and can be replaced within a couple of minutes through a load-lock. A two-microscope imaging system allows visual control of the jets from two perspectives. International Union of Crystallography 2019-02-22 /pmc/articles/PMC6412181/ /pubmed/30855241 http://dx.doi.org/10.1107/S1600577519000894 Text en © J. Schulz et al. 2019 http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.http://creativecommons.org/licenses/by/4.0/
spellingShingle Research Papers
Schulz, J.
Bielecki, J.
Doak, R. B.
Dörner, K.
Graceffa, R.
Shoeman, R. L.
Sikorski, M.
Thute, P.
Westphal, D.
Mancuso, A. P.
A versatile liquid-jet setup for the European XFEL
title A versatile liquid-jet setup for the European XFEL
title_full A versatile liquid-jet setup for the European XFEL
title_fullStr A versatile liquid-jet setup for the European XFEL
title_full_unstemmed A versatile liquid-jet setup for the European XFEL
title_short A versatile liquid-jet setup for the European XFEL
title_sort versatile liquid-jet setup for the european xfel
topic Research Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412181/
https://www.ncbi.nlm.nih.gov/pubmed/30855241
http://dx.doi.org/10.1107/S1600577519000894
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