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ME-Class2 reveals context dependent regulatory roles for 5-hydroxymethylcytosine

Since the discovery of 5-hydroxymethylcytosine (5hmC) as a prominent DNA modification found in mammalian genomes, an emergent question has been what role this mark plays in gene regulation. 5hmC is hypothesized to function as an intermediate in the demethylation of 5-methylcytosine (5mC) and in the...

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Detalles Bibliográficos
Autores principales: Schlosberg, Christopher E, Wu, Dennis Y, Gabel, Harrison W, Edwards, John R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412249/
https://www.ncbi.nlm.nih.gov/pubmed/30649543
http://dx.doi.org/10.1093/nar/gkz001

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